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A Review on Statistical Methods Using Longitudinal Biomarkers for Disease Early Detection

Yongli Han

Longitudinal biomarkers may be predictive for the early
detection of clinical outcomes. Tracking longitudinal
biomarkers as a way to identify early disease onset may
help to reduce mortality from diseases that are more
treatable if detected early. This review provides a brief
summary of a recent publication on statistical approaches
that use longitudinal biomarkers for disease early detection.
Comparison of statistical methods and future research
directions in general disease early detection using
longitudinal biomarkers are presented.