Navbir Pasricha
The Corpus Callosum (CC) is the largest commissural bundle with about 100 million fibres connecting the two cerebral hemispheres. It forms a massive arched interhemispheric bridge in the floor of the median longitudinal cerebral fissure. Researches have shown that it is involved in many advanced features of the brain, such as learning, memory, thinking, three-dimensional visual ability, executive functions as well as behavioural patterns. Inconsistencies lie regarding age related changes of Corpus Callosum. Despite rigorous investigations on age-related variations of CC, much controversy still exists in the literature. Morphometric analysis of normal Corpus Callosum is of value in the surgical interventions and stereotactic approaches to the foramen of Munro or third ventricle and in cases of callosectomy for intractable epilepsy. MR imaging is used for preoperative determination of the extent of callosectomy for epilepsy as well as for postoperative evaluation, especially T1 weighted images. Most of the published studies investigated age related CC variations in the western countries and few studies addressed it in any Southeast Asian country like India.
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