臨床小児皮膚科 オープンアクセス

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ユーロ小児科学 2020: 食事療法が注意欠陥多動性障害の結果に与える影響と血清スフィンゴシン-1-リン酸との関係 - ラニア・ナビル・サブリー - 国立研究センター

ラニア・ナビル・サブリ

目的:この調査では、食生活の変化がADHDの結果に与える影響、ADHD症状の促進因子としての食物の役割、および血清S1Pとの関連性を調査することを目的とした。

患者と方法:検査には、最近 ADHD と診断され、臨床的または行動的治療を受けていない、6~9 歳、IQ 70 以上、関連する合併症のない 47 名の若者が含まれていました。完全な病歴が収集され、5 週間の食事変更プログラム中に、臨床評価、人体計測、24 時間食事レビュー、食事調査、Conner の親の評価尺度更新簡易構造、および血清 S1P が行われました。

結果: 5 週間の食事変更プログラム後、コナーの親評価尺度更新版ショート フォーム (CPR-RS) で評価したところ、ADHD の症状に改善が見られました。食事変更プログラム後、でんぷんとタンパク質の摂取量が大幅に減少しました。食事変更プログラム後、エネルギー摂取量に実質的な変化は見られませんでしたが、脂肪摂取量は全体的に増加しました。ビタミン A、C、リボフラビン、チアミン、鉄の摂取量は食事変更プログラム後大幅に減少しましたが、推奨される食事制限範囲内でした。血清 S1P レベルは食事変更後大幅に減少しました。

結論:健康指導のヒントと食事変更プログラムに従うことで、CPR スコアの低下と血清 S1P の低下によって記録された ADHD の症状が改善しました。食事中のデンプンとタンパク質の摂取は、コナーの親評価尺度再考尺度 (CPR-RS) スコアと S1P と強く関連していました。

背景: Attention-shortfall/hyperactivity issue (ADHD) is a confusion set apart by a continuous example of heedlessness or potentially hyperactivity-impulsivity that meddles with working or advancement. Obliviousness implies an individual stray’s task, needs diligence, experiences issues continuing center, and is complicated; and these issues are not because of disobedience or absence of cognizance. Hyperactivity implies an individual appears to move about continually, remembering for circumstances in which it isn't proper; or exorbitantly squirms, taps, or talks. In grown-ups, it might be extraordinary eagerness or destroying others with consistent action. Impulsivity implies an individual makes hurried activities that happen at the time without first contemplating them and that may have a high potential for hurt, or a craving for guaranteed prizes or powerlessness to defer satisfaction. A hasty individual might be socially nosy and unreasonably intrude on others or settle on significant choices without thinking about the drawn out results. Carelessness and hyperactivity/impulsivity are the key practices of ADHD. A few people with ADHD just have issues with one of the practices, while others have both negligence and hyperactivity-impulsivity. Most kids have the joined kind of ADHD. Analysis of ADHD requires a far reaching assessment by an authorized clinician, for example, a pediatrician, therapist, or specialist with mastery in ADHD. For an individual to get a finding of ADHD, the side effects of negligence or potentially hyperactivity-impulsivity must be constant or dependable, disable the individual's working, and cause the individual to fall behind run of the mill advancement for their age. The specialist will likewise guarantee that any ADHD manifestations are not because of another clinical or mental condition. Most youngsters with ADHD get a conclusion during the grade school years. For a young adult or grown-up to get a determination of ADHD, the side effects need to have been available before age 12. ADHD indications can show up as right on time as between the ages of 3 and 6 and can proceed through puberty and adulthood. Manifestations of ADHD can be confused with passionate or disciplinary issues or missed altogether in peaceful, respectful youngsters, prompting a postponement in determination. Grown-ups with undiscovered ADHD may have a background marked by helpless scholastic execution, issues at work, or troublesome or bombed connections. ADHD side effects can change after some time as individual ages. In small kids with ADHD, hyperactivity-impulsivity is the most transcendent manifestation. As a kid arrives at grade school, the side effect of negligence may turn out to be progressively unmistakable and cause the youngster to battle scholastically. In pre-adulthood, hyperactivity appears to reduce and may show all the more regularly as sentiments of fretfulness or squirming, however negligence and impulsivity may remain. Numerous teenagers with ADHD likewise battle with connections and solitary practices. Negligence, eagerness, and impulsivity will in general persevere into adulthood. ADHD is one of the most widely recognized neurodevelopmental messes, influence 5% of youngsters worldwide and portrayed by weakening obliviousness, hyperactivity and impulsivity and can be maintained a strategic distance from by barring hazard factors, for example, food. Sphingosin-1-phosphate (S1P) is thought to have job in neuropsychiatric issues, immunological maladies/unfavorably susceptible responses and aggravations in its metabolic pathway were related with admission of certain nourishments and supplements

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