米国先進ドラッグデリバリージャーナル オープンアクセス

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Platelet Rich Fibrin- A New Hope for Regeneration of Osseous Defects in Aggressive Periodontitis Patients: A Case Report

Jayant R Ambulgekar, Rizwan M Sanadi, Manan Doshi and Priya Govalkar

Aggressive periodontitis causes rapid destruction of the periodontal attachment apparatus & the supporting alveolar bone. Early detection is critically important in the treatment of aggressive periodontitis because preventing further destruction is often more predictable than attempting to regenerate lost supporting tissues. Thus, the treatment of aggressive periodontitis must be pursued with a logical & regimented approach. A critical aspect of periodontal regeneration is the stimulation of the series of events & cascades at some point, which can result in the coordination & completion of integrated tissue formation. In general, a recent innovation in dentistry has been the preparation & use of platelet-rich fibrin (PRF), a concentrated suspension of growth factors found in platelets. These growth factors are involved in wound healing & postulated as promoters of tissue regeneration. It is both nontoxic & non immune-reactive. The use of PRF membrane in our case report to attain regeneration may alleviate the need for donor site procurement of bone graft.

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