欧州実験生物学ジャーナル オープンアクセス

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The effect of eight weeks of β-alanine supplementation and pyramid resistance training on carnosine and IL-8 in non-athlete men

Hamid Mohammadi Hossein Abady, Gholamreza Sharifi and Mohammad Faramarzi

The purpose of this research is determining The effect of eight weeks of β-alanine supplementation and pyramid resistance training on carnosine and IL- 8 in non-athlete men. In this job 40 young(ranging from 20 to 25 years old) non-athlete men were chosen and randomly sorted into 4 groups of " β-alanine supplementation" ," β-alanine supplementation consumption plus exercise" ,"placebo users" and "exercise besides the placebo";10 men for each. The resistance training were carries out for 8 weeks, 3 sessions each and up to the 70 to 90 percent of the intensity of a maximum frequency. The "only supplement" and "supplement plus exercise" groups each received 3.2 grams of supplement, 2 times during the 8 week research and the first group had three portions of exercise each week.The other 2 groups (the placebo & placebo beside the exercise) had the same pattern except they received the dextrin powder encapsulated in the similar capsules.Some measurements of hypertrophy (measuring the circumference of the breasts and the arms) and blood samplings were carried out to determine the levels of carnosine and IL-8, in 2 phases (one 24 hours before the test started and the other after the 8-weeks test was finished ).To check the changes from before until after the test, the "correlated t" was used and the one-way Analyse of Variance (ANOVA) in order to compare the 2 groups, and in case of observing significant results, the Bonferroni tracking test was based for the action.In this research the p, equal or less than (P≤0.05), was regarded as significant.The 8-weeks period of pyramid resistance training along with beta aniline supplement resulted in a significant levels of carnosine (p=0.01).interleukin8 levels were also rose but not so significant (p=0.46).In general, this research showed that pyramid resistance training along by beta aniline supplement ends to a significant carnosine and muscular hypertrophy in non-athlete men. And this is a reason for a rise in the volume of muscles, strength, and fatigue is reduced.