小児科および健康研究 オープンアクセス

抽象的な

Vitamin D role in osteopenia of prematurity... The concept story

 Said El deib

Osteopenia of prematurity  is a preventable disease. Improved survival of premature newborns is associated with an increased incidence of OOP. Osteopenia of prematurity is a metabolic bone disease of premature infants with birth weight < 1500 g and gestational age < 32 weeks. Sub-optimal bone matrix, and an increased risk of fractures characterized the disease. , multifactorial etiology and impact on early and late morbidity of the newborns. The prevention and treatment of bone disorders are important aspects of the care of preterm babies.

Objective: To diagnose the risk factors, to determine early diagnostic criteria and to create a prevention  osteopenia in infants with very low and extremely low birth weight.

In conclusion: Risk factors for osteopenia are: the low gestational age and low levels of vitamin D at birth. Biochemical markers of osteopenia are: changes in levels of parathyroid hormone, phosphorus and vitamin D at eight weeks of age. Prevention includes: early supplementation of vitamin D in the risk neonates with individual dose adjustment. Upon biochemical evidence of osteopenia treatment should begin in the second week of life with supplementation of phosphorus, and vitamin D daily  and appropriate physiotherapy.

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